The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms
Recruiting
N/AInterventional Study
Brain Injuries
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
130 (estimated)
Sponsor
The University of Texas Medical Branch, Galveston · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The aim of this study is to characterize the microbiome of patients undergoing post-acute residential neurorehabilitation compared to community controls and to determine if a dietary fiber, Inulin, can create a shift in the microbiome leading to changes in fatigue and cognition.
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Brain Injury Patients
Inclusion
* Ages 18 and above
* Admitted to Moody Neurorehabilitation Institute for care
* Less than 6 months post-injury
* English speaking
* Must be able to eat and drink by mouth
* Willing and able to comply with study procedures
* Willing and able to provide consent (with…
Brain Injury Patients
Inclusion
* Ages 18 and above
* Admitted to Moody Neurorehabilitation Institute for care
* Less than 6 months post-injury
* English speaking
* Must be able to eat and drink by mouth
* Willing and able to comply with study procedures
* Willing and able to provide consent (with LAR if needed)
Exclusion
* Significant heart, liver, kidney, blood or respiratory disease
* HIV, Hepatitis B or Hepatitis C
* Pregnancy or becoming pregnant during the study
* History of inflammatory bowel disease
* History of celiac disease
* Active diverticular disease
* Known allergy to study agent
* Any medical condition that, in the opinion of the investigator, would place the subject at increased risk for participation
Community Control Subjects
Inclusion
* Ages 18 and above
* Have a family member who is admitted to Moody Neurorehabilitation Institute for care OR is working at Moody Neurorehabilitation Institute
* English speaking
* Willing and able to comply with study procedures
* Willing and able to provide consent
* FACs score ≤ 50
Exclusion
* Trauma to head in last 6 months
* Stroke in last 6 months
* Significant heart, liver, kidney, blood or respiratory disease
* HIV, Hepatitis B or Hepatitis C
* Pregnancy or becoming pregnant during the study
* History of inflammatory bowel disease
* History of celiac disease
* Active diverticular disease
* Any medical condition that, in the opinion of the investigator, would place the subject at increased risk for participation
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.