ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study

Recruiting Phase 3 Interventional Study
Colon Cancer Colon Cancer (Stage II &Amp;Amp;Amp; III)
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
70 – 80
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
312 (estimated)
Sponsor
Zhejiang Cancer Hospital · Other
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About This Trial
The goal of this clinical trial is to explore the disease-free survival period of elderly patients with high-risk stage II and stage III colon cancer based on ctDNA detection. The main questions it aims to answer are: Can ctDNA detection effectively guide the assessment of disease-free survival in elderly patients with high-risk stage II and stage III colon cancer? What is the correlation between…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients aged 70-80, both male and female are eligible; 2. Patients with histopathologically confirmed stage II high-risk or stage III colon cancer; 3. Patients with an ECOG score of ≤2; 4. Patients who are required to undergo tissue genetic testing; 5. Subjects who voluntari…
Contacts

Yuping Zhu, M.D.

86-0571-88128011

drzyp@163.com

CONTACT

Yibo Cai, M.D.

86-0571-88128011

caiyiyibo@zju.edu.cn

CONTACT