Low-Intensity Focused Ultrasound for Essential Tremor

Ultrasound Neuromodulation in Essential Tremor

Recruiting N/A Interventional Study
Essential Tremor Neuromodulation
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
University of California, San Francisco · Other
Who this trial is looking for

This trial is looking for patients with severe tremors that have not responded to other treatments. Participants will receive a special ultrasound treatment aimed at specific parts of the brain to see if it helps reduce tremors.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have essential tremor that has not responded to other treatments.
  • I am scheduled for MR-guided high-intensity focused ultrasound thalamotomy.

You may not be able to join if

  • I have a pacemaker.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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Check Your Eligibility
About This Trial
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU c…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF. Exclusion Criteria: * Due to the logistical complexity of performing MRI in patients with MR-conditional pacemakers (n…
Contacts

Leo P. Sugrue, MD, PhD

415-353-9056

leo.sugrue@ucsf.edu

CONTACT

Tommaso Di Ianni, PhD

tommaso.diianni@ucsf.edu

CONTACT