Low-Intensity Focused Ultrasound for Essential Tremor
Ultrasound Neuromodulation in Essential Tremor
Recruiting
N/AInterventional Study
Essential TremorNeuromodulation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
University of California, San Francisco · Other
Who this trial is looking for
This trial is looking for patients with severe tremors that have not responded to other treatments. Participants will receive a special ultrasound treatment aimed at specific parts of the brain to see if it helps reduce tremors.
Are You a Good Fit for This Trial?
You may be able to join if
I have essential tremor that has not responded to other treatments.
I am scheduled for MR-guided high-intensity focused ultrasound thalamotomy.
You may not be able to join if
I have a pacemaker.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU c…
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF.
Exclusion Criteria:
* Due to the logistical complexity of performing MRI in patients with MR-conditional pacemakers (n…
Inclusion Criteria:
* Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF.
Exclusion Criteria:
* Due to the logistical complexity of performing MRI in patients with MR-conditional pacemakers (need for device and patient monitoring), patients with pacemakers will be excluded from enrollment. All other patients undergoing HIFU thalamotomy for tremor will be eligible for enrollment.
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