Effects of 60-day-6° Head-down Bed Rest on Cartilage and Function of the Knee Joint
Recruiting
N/A
Interventional Study
Cartilage Degeneration
Weightlessness
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 25 – 50
- Sex
- Male
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 26 (estimated)
- Sponsor
- Peking University Third Hospital · Other
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About This Trial
Objective: To investigate the effects of long-term simulated unloading in bed on articular cartilage quality based on functional magnetic resonance imaging (FMRI) and Knee joint function.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* (1) male; (2) age 25-50 years old; (3) height between 160-175 cm, weight ≥50kg, and BMI between 18.5-26 kg/m²; (4) good general health status.
Exclusion Criteria:
* (1) history of alcoholism; (2) smoking ≥5 cigarettes/day in the 3 months before the test; (3) drug dependence …
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