Left Bundle Branch Area Pacing or Biventricular Pacing in AF and Left Ventricular Dysfunction

Recruiting N/A Interventional Study
Heart Failure Block, Heart Pacing-Induced Cardiomyopathy
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
34 (estimated)
Sponsor
srdpiers · Other
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About This Trial
It is unknown whether left bundle branch area pacing (LBBAP) or biventricular pacing best prevents or reverses left ventricular (LV) adverse remodelling in patients with atrial fibrillation (AF) who require ventricular pacing or CRT. This randomized non-inferiority cross-over trial will compare left ventricular end-systolic volume change and secondary endpoints between LBBAP and biventricular paci…
Trial Locations
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Eligibility Criteria
INCLUSION CRITERIA In order to be eligible to participate in this study, a subject must meet all of the following criteria: * Adults ≥18 years with permanent AF and LVEF \< 50% who either require ventricular pacing because of bradycardia including patients undergoing AV junction ablation, or ha…
Contacts

Sebastiaan RD Piers, MD, PhD

+31715262020

s.r.d.piers@lumc.nl

CONTACT