No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 50
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
100 (estimated)
Sponsor
University of Illinois at Chicago · Other
Who this trial is looking for
This trial is looking for adults with type 1 diabetes who have trouble with their sleep patterns and want to improve them. Participants will help researchers understand how better sleep affects diabetes and heart health.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 50 years old
I have been diagnosed with type 1 diabetes for at least one year
I usually have irregular sleep patterns of more than one hour a week
I want to improve my sleep
I own a smartphone
You may not be able to join if
My A1C level has been 10% or higher in the past 6 months
I have insomnia symptoms
I have a history of restless leg syndrome
I have had severe low blood sugar in the past 6 months
I regularly work night shifts or sleep after 3 AM
I use sleep medications or have serious other health issues
I have depression
I am pregnant, breastfeeding, or planning to become pregnant
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
People with type 1 diabetes are disproportionately affected by cardiovascular disease (CVD). Short and irregular sleep have been associated with cardiovascular risk in this population. Improving sleep regularity has been associated with improved glycemic markers however mechanisms by which improving sleep regularity improves metabolic and cardiovascular health is not known. The investigators propo…
People with type 1 diabetes are disproportionately affected by cardiovascular disease (CVD). Short and irregular sleep have been associated with cardiovascular risk in this population. Improving sleep regularity has been associated with improved glycemic markers however mechanisms by which improving sleep regularity improves metabolic and cardiovascular health is not known. The investigators propose to conduct a mechanistic study using a sleep stability manipulation. This proposal will advance the understanding of mechanisms by which improving sleep regularity influences glycemic control and cardiovascular risk in T1D.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Adults 18-50 years with a clinical diagnosis of T1D for at least one year
* Report habitual sleep irregularity ≥1 hour/week
* Desire to improve sleep, and own a smartphone (Android or iPhone)
Exclusion Criteria:
* Self-reported A1C within the past 6 months ≥10%
* insomnia sy…
Inclusion Criteria:
* Adults 18-50 years with a clinical diagnosis of T1D for at least one year
* Report habitual sleep irregularity ≥1 hour/week
* Desire to improve sleep, and own a smartphone (Android or iPhone)
Exclusion Criteria:
* Self-reported A1C within the past 6 months ≥10%
* insomnia symptoms defined as Insomnia Severity Index score ≥15
* history of restless leg syndrome
* history of severe hypoglycemia (defined as hypoglycemic episode that results in loss of consciousness, seizure, or requiring emergency room visit or hospitalization) within the past 6 months
* rotating shift or night work or routinely sleeping after 3 AM.
* use of sleep medications/aids, significant medical comorbidities (such as heart failure, cirrhosis, chronic obstructive pulmonary disease requiring oxygen, active treatment for cancer, on renal replacement therapy \[dialysis\])
* depression (Patient Health Questionnaire 8 \[PHQ-8\] score ≥15)
* history of stroke with neurological deficits
* pregnant, breast feeding, or planning pregnancy, as sleep and glucose are known to change during pregnancy and breastfeeding.
* Allergy to lidocaine Participants who passed the first screen by phone will be scheduled for a consenting visit at UIC
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