Evaluation of Analgesia for Cardiac Elective Surgery in Children

Recruiting Phase 3 Interventional Study
Pediatric Cardiac Surgery
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
3 – 18
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Treatment
Participants needed
500 (estimated)
Sponsor
Senthil Sadhasivam · Other
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About This Trial
The purpose of this study is to look at a standardized methadone-based enhanced recovery after surgery protocol following pediatric cardiac surgery. This study will consist of randomly assigning children to receive the methadone-based recovery procedures or to receive current standard of care recovery procedures. Randomly assigning means that there is a 50/50 chance, like a coin flip, of being ass…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Children aged 3-years - \<18 years * ASA physical status 1, 2, or 3 * Participant or legal guardian can speak and read English or Spanish * Undergoing the following cardiac surgeries (Categories 1 \& 2) that are associated with significant acute surgical pain STS Category 1: …
Contacts

Senthilkumar Sadhasivam, MD,MPH, MBA, FASA

4126474484

sadhasivams@upmc.edu

CONTACT

Dayana Alsamsam, BSPS, MSc

alsamsamd@upmc.edu

CONTACT