Liberal or Adhere to Recommendations for PCC Management in Major Bleeding Following Trauma
Recruiting
N/A
Interventional Study
Traumatic Bleeding
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 650 (estimated)
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine · Other
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About This Trial
Severe post-traumatic bleeding remains a major challenge in trauma management . The effectiveness and safety of PCC in the treatment of major traumatic bleeding is controversial, and the indications for use are not clear. Studies on the status of PCC use and the efficacy evaluation of PCC adhere to recommendations are lacking.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age ≥18 years old or \< 80 years old
2. Trauma treated in resuscitation unit/emergency room patient
3. Hospital admission within 24h after injury
4. Assessment of blood consumption (ABC) score ≥2 points.
Exclusion Criteria:
1. PCC was used before admission
2. Anticoagulant …
Contacts