Screening Strategies Among High-risk Populations for Anal Cancer
Recruiting
N/A
Interventional Study
Neoplasms
HPV-Related Anal Squamous Cell Carcinoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 30 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Screening
- Participants needed
- 500 (estimated)
- Sponsor
- Lisa Flowers · Other
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About This Trial
The goal of the proposed research is to 1) examine the performance of emerging screening methods for anal high-grade squamous intraepithelial lesion (aHSIL), a precancerous condition of anal cancer, among populations at high risk for anal cancer and 2) characterize DNA methylation, immunologic response, and environmental factors associated with aHSIL.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 30-80 years of age
* Individuals with chronic impaired immune status
* History of high-grade lower genital tract neoplasia (LGTN), Zubrod Performance Status of 0-2;
Exclusion Criteria:
* Patients treated for aHSIL less than 6 months before screening,
* History of anal cancer…
Contacts