IMRT Versus IMPT With Concurrent Chemotherapy for Locally Advanced Anal Canal Cancer
Recruiting
N/A
Interventional Study
Malignant Neoplasm of Anal Canal
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 108 (estimated)
- Sponsor
- Tata Memorial Centre · Other
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About This Trial
The standard practice in management of carcinoma of anal canal is to treat patients with radiotherapy using the IMRT technique along with chemotherapy. It is known that while IMRT has reduced treatment related side effects as compared to the older radiation techniques, reducing these side effects further still remains a major challenge.
These side-effects include gastrointestinal (diarrhea, alter…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age \> 18 and \< 80 years of age
2. Histologically confirmed squamous cell carcinoma of the anal canal or distal rectum
3. The patients may have TNM stage T1-2 N+M0 or T3-4 N0-1c M0 (UICC 8th edition)
4. Involvement of lower para-aortic lymph nodes (till renal hilum) as the o…
Contacts