Inflammatory Challenge and Fear

Recruiting Phase 1 Interventional Study
Posttraumatic Stress Disorder (PTSD)
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 60
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
288 (estimated)
Sponsor
University of California, San Francisco · Other
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About This Trial
The goal of this study is to learn if short-term changes in the immune system alter how we process information and experience fear. The main questions it aims to answer are: Do people who receive typhoid vaccine respond differently than those who receive a placebo saline vaccine? Do people who receive typhoid vaccine experience changes in how they think and feel? Participants will: Attend four …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: All Subjects: 1. Aged 18-60 years old 2. Trauma Exposed 3. Current PTSD/No history of PTSD Exclusion Criteria: 1. Contraindications to typhoid vaccine 2. Conditions associated with inflammation 3. Pregnancy or plans to become pregnant in next three months
Contacts

Aoife O'Donovan, PhD

415-221-4810

aoife.odonovan@ucsf.edu

CONTACT

Michael Srouji, BA

415-221-4810

CONTACT