Catheter Ablation for Atrial Fibrillation and Mitral Regurgitation

Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation

Recruiting Observational Study
Atrial Fibrillation (AF) Atrial Functional Mitral Regurgitation
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 80
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
Second Affiliated Hospital, Zhejiang University, School of Medicine · Other
Who this trial is looking for

This trial is looking for patients with atrial fibrillation and specific heart conditions. Participants will receive either catheter ablation treatment or drug therapy and will be monitored over time.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 80 years old
  • I have been diagnosed with symptomatic paroxysmal atrial fibrillation
  • I have moderate to severe mitral regurgitation and normal heart function
  • I understand the trial and can give my consent to participate
  • I can attend follow-up visits as required

You may not be able to join if

  • I have atrial fibrillation due to reversible causes like thyroid disease
  • I have active endocarditis or severe mitral stenosis
  • I have left atrial or left atrial appendage thrombosis
  • My left ventricular ejection fraction is below 50%
  • I have had heart surgery involving my left atrial appendage
  • I have a device like a pacemaker or defibrillator implanted
  • I am pregnant, breastfeeding, or cannot use contraception
  • I have a life expectancy of less than 12 months

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

To evaluate the improvement of mitral regurgitation after catheter ablation of atrial fibrillation or regular drug therapy in atrial fibrillation patients combined with atrial functional mitral regurgitation.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients aged 18 to 80 years old; 2. Patients diagnosed with symptomatic paroxysmal atrial fibrillation (AF history \< 5 years) 3. Moderate to severe MR and normal LV ejection fraction (≥50%), LVEDD\<55 mm, and normal LV wall systolic function 4. Able to underst…
Contacts

Xianbao Liu, Dorctor

086-571-87784705

liuxb@zju.edu.cn

CONTACT