Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT
Recruiting
Observational Study
CancerThoracic CancerGynecologic CancerHead and Neck CancerGastrointestinal Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
125 (estimated)
Sponsor
University of California, San Francisco · Other
Who this trial is looking for
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Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemotherapy and radiation therapy (CCRT) and to develop and assess predictive models for CRF severity.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Participants have not received any prior treatment (i.e., cancer systemic therapies or radiation therapy) in the month except surgery or inductive Chemotherapy (CTX).
* Participants receiving \>= 15 fractions.
* Participants is male or female and is \>18 years of age on the da…
Inclusion Criteria:
* Participants have not received any prior treatment (i.e., cancer systemic therapies or radiation therapy) in the month except surgery or inductive Chemotherapy (CTX).
* Participants receiving \>= 15 fractions.
* Participants is male or female and is \>18 years of age on the day of signing the informed consent.
* Ability to understand a written informed consent document.
* Able and willing to complete all of the study questionnaires and provide blood and stool samples prior to, midway, and following the completion of treatment.
* Willing to have medical records reviewed for clinical information.
* Able to read, write and understand English or Spanish.
Exclusion Criteria:
* Contraindication to phlebotomy for removal of approximately 50 mL of peripheral blood within 6 week period (Institutional Review Board (IRB) limit).
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