In this study, a 12-week pragmatic, randomized, double-blinded clinical trial will be conducted to evaluate the efficacy of acupuncture for the treatment of long Covid neuropsychiatric symptoms and provide reference for clinical non-drug treatment.
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Eligibility Criteria
Inclusion Criteria:
* meet the clinical diagnosis of Long COVID by the World Health Organization (WHO), with no neuropsychiatric symptoms 1 year before infection with Covid-19, and continue to have at least one neuropsychiatric symptom for 2 months after SARS-CoV-2 turned negative 3 months above;
*…
Inclusion Criteria:
* meet the clinical diagnosis of Long COVID by the World Health Organization (WHO), with no neuropsychiatric symptoms 1 year before infection with Covid-19, and continue to have at least one neuropsychiatric symptom for 2 months after SARS-CoV-2 turned negative 3 months above;
* aged 12 to 80 years;
* willing and able to consent, and complete all assessment and study procedures
Exclusion Criteria:
* patients with a history of chronic neuropsychiatric symptoms;
* cardiovascular diseases pre-existing to the Covid-19 episode such as arrhythmia, heart failure, myocardial infarction, and patients with cardiac pacemakers;
* documented pre-existing history of psychiatric illness, including substance abuse;
* suicidal tendencies (attempted suicide in the 12 months before the study);
* any chronic or remote neurological disorder (i.e. stroke, head trauma, epilepsy, tumor);
* those who participated in other clinical trials within one month;
* pregnant or lactating female patients;
* have surgery within two months before the study or will have a scheduled surgery during the study;
* acute brain injury or acute encephalopathy from another etiology than Covid-19 (e.g., sepsis, liver or renal failure, alcohol or drug withdrawal, drug toxicity);
* open-heart cardiac surgery or cardiac arrest during the last 6 months;
* patients who received acupuncture treatment 1 month before the start of the study;
* patients who were unable to complete the assessment during screening due to severe mental, cognitive, or emotional impairment
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