Episwitch CiRT® Test for Advanced Cancer Treatment

A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.

Recruiting Observational Study
Cancer Immunotherapy PD-1 PD-L1 Immune Checkpoint Therapy
No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
2,000 (estimated)
Sponsor
Oxford Biodynamics Inc. · Industry
Who this trial is looking for

This trial is looking for adults with stage III or IV cancer to participate in research using a blood test to help understand how well they might respond to certain cancer treatments. Participants will need to follow specific requirements and provide consent to join.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am 18 years of age or older
  • I have stage III or IV cancer
  • My doctor has selected me for the Episwitch CiRT® test
  • I can understand and provide written consent
  • I am clinically eligible for immune checkpoint inhibitor therapy
  • I have an ECOG performance status of 2 or less
  • I am willing to comply with study requirements

You may not be able to join if

  • I am pregnant or breastfeeding
  • I have a history of bone marrow or organ transplant
  • I have a contraindication for immune checkpoint inhibitor therapy

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this research is to test whether a blood-based 3D genome conformation mapping test called the Episwitch CiRT® can help to identify likelihood of response to PD-(L)-1 checkpoint inhibitors (a class of cancer drugs) across multiple oncological indications by comparing the results to actual treatment responses for cancer patients.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. 18 years of age or older 2. Stage III or IV cancer 3. Selected by their healthcare provider to receive the Episwitch CiRT® test according to the current evidence-based schedule (per protocol) as part of their standard of practice. 4. ECOG performance status ≤ 2 5. Clinically …
Contacts

Ryan Mathis, MD

888-200-3361

ryan.mathis@myobdx.com

CONTACT

Joseph DeSimone, BA

803-329-7772

joseph@ccorn.net

CONTACT