Psyllium in Pediatric IBS

Recruiting Phase 2 Interventional Study
Irritable Bowel Syndrome
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
12 – 17
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
110 (estimated)
Sponsor
Dr Bruno Chumpitazi, M.D. · Other
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About This Trial
The goal of this clinical trial is to learn if a fiber (psyllium) can change the way bacteria use fructans (a type of sugar) and whether psyllium can help decrease childhood irritable bowel syndrome (IBS) symptoms when eating fructans. The main questions it aims to answer are: Aim 1: The effect of psyllium at two doses given with a fructan meal on microbial fructan fermentation (intracolonic pH; …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Children between the ages of 12-17 years meeting pediatric Rome IV criteria for IBS Exclusion Criteria: * Children who have had previous bowel surgery, have documented GI disorders (e.g., ulcerative colitis), or a serious chronic medical condition (e.g., diabetes) * weight a…
Contacts

Bruno Chumpitazi, MD, MPH

919-660-1227

bruno.chumpitazi@duke.edu

CONTACT

Annette Babu

919-660-1227

annette.babu@duke.edu

CONTACT