AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
Recruiting
N/A
Interventional Study
HFpEF - Heart Failure With Preserved Ejection Fraction
Atrial Fibrillation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 99
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 40 (estimated)
- Sponsor
- Technical University of Munich · Other
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About This Trial
The investigators analyze the impact of exercise and ablation in patients with symptomatic short-persistent atrial fibrillation (Afib) and heart failure with preserved ejection fraction (HFpEF). It is hypothesized that the combination of ablation and exercise better improves peak oxygen consumption (VO2peak) through improvement of peripheral (exercise training) and central (ablation) adaptations.
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Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosed heart failure with preserved ejection fraction
* Symptomatic short-persistent atrial fibrillation (diagnosis within 1 year of study inclusion)
Exclusion Criteria:
* Paroxysmal, long-persistent or permanent atrial fibrillation
* Clinically unstable coronary artery d…
Contacts