Expanded Hemodialysis for Kidney Failure
DIALysis With EXpanded Solute Removal
Recruiting
N/A
Interventional Study
Chronic Kidney Disease Requiring Hemodialysis
End-Stage Kidney Disease (ESKD)
Chronic Kidney Disease Requiring Chronic Dialysis
Pragmatic Randomized Controlled Trial
Kidney Disease
Renal Insufficiency, Chronic
Kidney Failure, Chronic
Hemodialysis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 45 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 4,800 (estimated)
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Other
Who this trial is looking for
This trial is looking for patients who have been receiving hemodialysis regularly. Participants will continue their usual treatments while comparing two types of dialysis filters to see if one improves health outcomes.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 60 years or older
- I am 45 to 59 years old with a history of diabetes
- I have been on dialysis for at least the last 90 days
- I receive in-centre hemodialysis 3 or more times a week
- I have a valid health insurance card
You may not be able to join if
- My doctor thinks I am not appropriate for this study
- I have known intolerance to the Nipro Elisio HX dialyzer
- I plan to receive HDF or nocturnal HD
- I might stop in-centre HD in the next 3 months
- I cannot follow my dialysis treatment schedule
- I have a strong preference for expanded HD
- I am currently in another clinical trial that conflicts with this one
- I have previously participated in this trial
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The goal of this clinical trial is to evaluate the health effects of expanded hemodialysis in patients receiving hemodialysis. The main question it aims to answer is:
1\) Does expanded hemodialysis reduce the risk of death from any cause?
Researchers will compare expanded hemodialysis to conventional hemodialysis (the treatment currently used for the majority of patients receiving hemodialysis) …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Inclusion requires that all the following are present:
1. One of:
1. Age 60 years or older; or
2. Age 45 to 59 years with a history of diabetes mellitus (Type 1 or Type 2) regardless of current glycemic status; and
2. Receiving any form of dialysis regularly for the previ…
Contacts