Sintilimab Combined SBRT As Neoadjuvant Therapy for Resectable HCC with PVTT
Recruiting
Phase 2
Interventional Study
Hepatocellular Carcinoma (HCC)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 33 (estimated)
- Sponsor
- West China Hospital · Other
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About This Trial
The goal of this single-arm, prospective clinical trial is to evaluate the safety and efficacy of neoadjuvant therapy combining sintilimab with stereotactic body radiation therapy (SBRT) in patients with resectable hepatocellular carcinoma (HCC) with branch portal vein tumor thrombus. The main questions it aims to answer are:
1. Is the combination of sintilimab and SBRT safe as neoadjuvant therap…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age greater than 18 years, regardless of gender.
* Voluntary participation, as evidenced by signed informed consent, with the willingness and ability to comply with scheduled visits, treatment plans, laboratory tests, and other study procedures.
* Diagnosis of hepatocellular c…
Contacts