Use Misoprostol to Optimize Prevention of Cervical Cancer

Recruiting N/A Interventional Study
Cervical Cancers
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
25 and older
Sex
Female
Study type
Interventional
Purpose
Screening
Participants needed
420 (estimated)
Sponsor
University of Alabama at Birmingham · Other
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About This Trial

This is a double-blind randomized controlled trial of 420 non-pregnant women undergoing cancer screening by visual inspection with acetic acid (VIA) who have Type 3 transformation zone (TZ) and randomized to receive either Misoprostol or placebo.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Diagnosis of Type 3 TZ confirmed on exam prior to randomization * Age 25 years or older Exclusion Criteria: * With Type 1 or 2 TZ prior to randomization * Currently pregnant * History of hysterectomy * Any cancerous lesions * Active cervicitis
Contacts

Warner K Huh, MD

2059341555

whuh@uabmc.edu

CONTACT

Simon M Manga, PhD

2059345612

smanga@uab.edu

CONTACT