Evaluation of Endothelial Glycocalyx in the Surgical Resuscitation of Major Burn Patients
Recruiting
Observational Study
Syndecan 1
Severe Burn
Endotheliopathy of Trauma
Endothelial Glycocalyx
Hemorrhagic Shock
Postoperative Complications
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 40 (estimated)
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute · Other
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About This Trial
The purpose of this observational study is to examine whether Endotheliopathy of Trauma (EoT) is present in severely burned patients and how it is affected by burn debridement surgery.
The main questions it aims to answer are:
* Do severely burned patients present with EoT before undergoing burn debridement surgery?
* Does the surgical intervention worsen EoT, leading to increased postoperative …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients over 18 years old with burned TBSA greater than or equal to 20%.
* Patients who will undergo debridement of at least 20% of the burned TBSA (including the debrided area and the donor site).
Exclusion Criteria:
* Under 18 years old.
* Pregnant women.
* Patient refusa…
Contacts