Fasting Mimicking Diet with Immunotherapy for Lung Cancer

Evaluating a Fasting-mimicking Diet in Combination With Immunotherapy in Patients With Non-small Cell Lung Cancer

Recruiting N/A Interventional Study
Stage IV NSCLC NSCLC Immunotherapy Fasting Mimicking Diet
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
66 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for

This trial is looking for patients with advanced lung cancer to see how a special diet affects cancer cells during treatment. Participants will follow a fasting-like diet while receiving standard immunotherapy.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am at least 18 years old.
  • I have been diagnosed with stage IV Non-Small Cell Lung Cancer.
  • My performance status is between 0 and 2.
  • I have a body mass index (BMI) of 19 or higher.
  • I will start immunotherapy for my cancer soon.
  • I will receive a PD-L1 inhibitor as my immunotherapy treatment.

You may not be able to join if

  • I have lost more than 10% of my weight in the last 6 weeks.
  • I have a history of severe low blood sugar or uncontrolled diabetes.
  • I have used certain drugs that affect insulin growth factors.
  • I take immunosuppressive medications like prednisone or azathioprine.
  • I have significant food allergies that prevent me from eating the trial food.
  • I have any uncontrolled medical or mental health condition.
  • I am pregnant or breastfeeding.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this study is to learn the effects of fasting on cancer cells while you get maintenance treatment.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * 18 years at the time of informed consent * Ability to provide written informed consent and HIPAA authorization. * Eastern cooperative group (ECOG) performance status of 0 to 2 * Newly diagnosed histologically or cytologically confirmed stage IV Non-Small Cell Lung Cancer (NSCL…
Contacts

Shadia Jalal, MD

(317) 274-5500

Shadia.Jalal@va.gov

CONTACT

Aleksandra Radovanovich, RN

(317) 988-3338

aleksandra.radovanovich@va.gov

CONTACT