Weight Management Program for Obesity in Teens

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Recruiting Phase 3 Interventional Study
Obesity Overweight
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
6 – 17
Sex
Any
Trial phase
Phase 3
Study type
Interventional
Purpose
Screening
Participants needed
125 (estimated)
Sponsor
Eli Lilly and Company · Industry
Who this trial is looking for

This trial is looking for teens aged 12 to under 18 who are struggling with obesity or being overweight. Participants must have tried losing weight before but were unsuccessful.

Are You a Good Fit for This Trial?
Rules you out Type 1 diabetesMedullary thyroid carcinomaMultiple Endocrine Neoplasia Syndrome Type 2

You may be able to join if

  • I am aged between 12 and under 18
  • I have a BMI at or above the 95th percentile for my age and sex
  • I have a BMI at or above the 85th percentile but less than the 95th percentile for my age and sex and have at least one weight-related health issue
  • I have tried to lose weight with a structured program before and was not successful

You may not be able to join if

  • I have had weight loss surgery or plan to have one
  • I have a secondary cause of obesity
  • I have lost more than 5 kg in the last 90 days
  • I have type 1 diabetes or a history of severe diabetes complications
  • My HbA1c is above 9.0%
  • I have a family or personal history of certain thyroid cancers

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The purpose of this pediatric, chronic weight management, Phase 3 Master Protocol (PWMP) is to create a framework to evaluate the safety and efficacy of pharmacologic agents for the treatment of obesity or overweight in pediatric participants.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Have a history of at least 1 unsuccessful effort to lose sufficient body weight after participation in a structured lifestyle modification program (diet and exercise counseling for at least 3 months) prior to screening. * Obesity as defined by BMI equal to or above the 95th pe…
Contacts

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or

1-317-615-4559

LillyTrials@Lilly.com

CONTACT

Physicians interested in becoming principal investigators please contact

clinical_inquiry_hub@lilly.com

CONTACT