Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification
Recruiting
Observational Study
Headache (Migraine)MigraineMigraine HeadacheMigraine with AuraMigraine Without AuraEpisodic MigraineChronic Migraine HeadacheChronic Migraine, HeadacheEpisodic Migraine Headache
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
6 – 75
Sex
Any
Study type
Observational
Participants needed
440 (estimated)
Sponsor
Hospital Universitari Vall d'Hebron Research Institute · Other
Who this trial is looking for
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Patients will be asked to visit the study center 2 times, the first time for clinical assessment and a second time for sample collection. Healthy controls will only be asked to visit the study center for sample collection. A sample of blood and saliva will be collected in order to measure CGRP levels and DNA and hormone testing.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Migraine patients according to ICHD-3 criteria
* Healthy controls paired to patient age and sex, without headache and without first degree family history of headache.
Exclusion Criteria:
* Presence of any major medical or neurological illness.
* Presence of any salivary glan…
Inclusion Criteria:
* Migraine patients according to ICHD-3 criteria
* Healthy controls paired to patient age and sex, without headache and without first degree family history of headache.
Exclusion Criteria:
* Presence of any major medical or neurological illness.
* Presence of any salivary gland malfunction.
* Abuse or dependence to tobacco, alcohol or any drug in the previous 12 months before the enrollment.
* Active migraine preventive treatment.
* Pregnant or breastfeeding female.
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