No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
UNC Lineberger Comprehensive Cancer Center · Other
Who this trial is looking for
This trial is looking for adult cancer patients who are referred to oncology clinics. Participants will take part in a pre-treatment rehabilitation program to help improve their health and quality of life during cancer treatment.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old.
I have been referred to cancer care at the University of North Carolina Medical Center.
I can comply with study procedures.
I have answered 'yes' to at least one health screening question.
You may not be able to join if
I cannot read or understand English.
I have a psychological or other disability preventing me from giving consent.
I have a medical condition that makes it unsafe for me to exercise.
I am a prisoner or live in an institution.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This pilot health services interventional study aims to prospectively assess the effectiveness of a pre-treatment rehabilitation (prehabilitation) program across a diverse cohort of adult cancer patients via a randomized pilot trial. Upon screening and identification of high-risk features through a central navigation process, patients referred to oncology clinics will be approached to participate …
This pilot health services interventional study aims to prospectively assess the effectiveness of a pre-treatment rehabilitation (prehabilitation) program across a diverse cohort of adult cancer patients via a randomized pilot trial. Upon screening and identification of high-risk features through a central navigation process, patients referred to oncology clinics will be approached to participate in tailored prehabilitation interventions. The study will track and analyze functional outcomes and quality of life aiming to demonstrate the comprehensive benefits of prehabilitation on the cancer treatment continuum. We hypothesize that this referral program is feasible and that those randomized to the intervention arm will have superior functional outcomes and global health-related quality of life.
The rationale for this study is anchored in the urgent need to optimize the cancer care trajectory for high-risk patients whose treatment outcomes and quality of life are jeopardized by the multifaceted challenges of their disease. While prehabilitation has shown potential to mitigate these adverse effects, the optimal methods for identifying and connecting these high-risk individuals to appropriate prehabilitation resources remain underexplored. This study, with its systematic approach to enrolling a diverse adult cancer population, endeavors to investigate not only the benefits of prehabilitation interventions but also the effectiveness of a targeted referral process. By doing so, it aims to uncover novel strategies for efficiently allocating prehabilitation resources, thereby enhancing the precision and impact of supportive cancer care.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Written informed consent obtained to participate in the study and HIPAA authorization for the release of personal health information.
* Subjects are willing and able to comply with study procedures based on the judgement of the investigator.
* Age ≥ 18 years at the time of con…
Inclusion Criteria:
* Written informed consent obtained to participate in the study and HIPAA authorization for the release of personal health information.
* Subjects are willing and able to comply with study procedures based on the judgement of the investigator.
* Age ≥ 18 years at the time of consent.
* The subject has been screened by the Central Oncology Navigation Program and referred to cancer care at the University of North Carolina Medical Center.
* Answer "yes" to at least one of the following screening questions:
1. Does your health interfere with any of your activities of daily living (ADLs)?
2. Have you fallen, or do you feel unsteady while standing or walking?
3. Do you use durable medical equipment (DME)?
4. Are you interested in increasing the amount you exercise?
Exclusion Criteria:
* Inability to read and understand the English language.
* Psychological or other disability resulting in the inability to provide informed consent.
* Unstable medical comorbidity that precludes safe participation in an exercise program, in the judgment of the clinical investigator.
* Prisoners and other institutionalized individuals.
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