Study on the Effect of Atorvastatin Co-administered With Omeprazole on Statin Lactone
Recruiting
Phase 4
Interventional Study
Metabolite
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 21 – 75
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 78 (estimated)
- Sponsor
- National University Hospital, Singapore · Other
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About This Trial
This is a 2-arm, prospective, randomized, parallel-group, open-label, longitudinal study that lasts 30 days for each study participant. This study aims to investigate the effect of co-administration of Omeprazole with Atorvastatin versus Atorvastatin monotherapy on atorvastatin lactone level.
Primary endpoint: Higher statin lactone level in intervention arm after 30 days.
Secondary endpoints:
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Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Males between 21 and 75 years old or females between 50 and 75 years old
* No contraindications to the use of Atorvastatin amp; Omeprazole.
* Ability to comply with study requirements eg administer Atorvastatin and Omeprazole once daily and return for follow-up 1 month later.
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Contacts