Negative Emotionality and Epigenetics During Puberty

Recruiting Observational Study
Puberty Healthy Stress
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
8 – 17
Sex
Female
Study type
Observational
Participants needed
100 (estimated)
Sponsor
International Research Training Group 2804 · Other
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About This Trial
Pubertal transition leads to enduring neuroendocrine changes along with changes in the epigenome. The prevalence of psychiatric disorders significantly increases in females compared to males after puberty. There is likely to be an interaction between epigenetics, hormones and neurophysiological processes during puberty, leading to the increased prevalence of mental disorders in females. This study…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * healthy girls * aged between 8-10 and having pubertal stage 1 or between 15-17 and having pubertal stage 5 * normal body mass index according to age (between 5th and 85th percentile) * non-smoking * German language fluency * Attending age-appropriate schools Exclusion Criteri…
Contacts

Vanessa Nieratschker, Prof. Dr.

+497071-2985523

vanessa.nieratschker@med.uni-tuebingen.de

CONTACT

Birgit Derntl, Prof. Dr.

+497071 29-85437

birgit.derntl@med.uni-tuebingen.de

CONTACT