Time-restricted Eating Acceptability, Efficacy and Safety in Obesity
Recruiting
N/AInterventional Study
Time Restricted Eating
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
19 – 65
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
46 (estimated)
Sponsor
University of Mississippi, Oxford · Other
Who this trial is looking for
This trial is looking for adults aged 19 to 65 who are living with obesity. Participants will try a specific eating schedule for 8 weeks while being monitored for various health outcomes.
Are You a Good Fit for This Trial?
Rules you outType 1 diabetesType 2 diabetesHeart diseaseHypertensionEating disorders
You may be able to join if
I am between 19 and 65 years old.
I have a body mass index (BMI) of 25 or higher.
I have a high body fat percentage.
I lead a sedentary lifestyle.
I own a smartphone.
I usually eat for at least 12 hours each day.
I am apparently healthy.
You may not be able to join if
I have been diagnosed with diabetes.
I have heart disease or heart failure.
I have uncontrolled high blood pressure.
I have a history of significant weight change recently.
I have had any kind of weight-loss surgery.
I am currently on hormone replacement therapy.
I have an eating disorder.
I smoke or have an addiction to alcohol or drugs.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
A randomized controlled trial to determine adherence, acceptability and safety of time restricted eating (TRE) in healthy, sedentary, free-living adults with obesity between the ages of 19-65 years when following 16:8 TRE for 8 weeks. This 9-week study includes a baseline week and 8 weeks of the intervention period. Participants are randomly assigned to the TRE or the non-fasting control group. Th…
A randomized controlled trial to determine adherence, acceptability and safety of time restricted eating (TRE) in healthy, sedentary, free-living adults with obesity between the ages of 19-65 years when following 16:8 TRE for 8 weeks. This 9-week study includes a baseline week and 8 weeks of the intervention period. Participants are randomly assigned to the TRE or the non-fasting control group. The TRE group will consume calorie containing food and drink only over an 8 hour period and rest of the 16 hour would be fasting. Adherence to TRE and calorie intake are the primary outcomes. Motivators, facilitators and barriers to TRE, hunger and cravings levels, weight bias internalization, body composition (weight, body fat%, fat mass and muscle mass) , Healthy Eating Index (HEI) to assess diet quality, skin carotenoid levels, disordered eating risk, sleep quality, and perceptions of health and well-being are secondary outcomes.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 19 to 65 years
* Owns a smartphone
* Apparently healthy
* BMI ( more than or equal to 25 kg/m2 ) and high body fat percent (BF%) (≥25% and ≥35% for males and females, respectively)
* Sedentary lifestyle (less than 150 minutes of self-reported moderate to vigorous activity …
Inclusion Criteria:
* Age 19 to 65 years
* Owns a smartphone
* Apparently healthy
* BMI ( more than or equal to 25 kg/m2 ) and high body fat percent (BF%) (≥25% and ≥35% for males and females, respectively)
* Sedentary lifestyle (less than 150 minutes of self-reported moderate to vigorous activity per week)
* Self-reported eating interval of ≥12 h per day
Exclusion Criteria:
* Diagnosed diabetes mellitus (type I or II), coronary heart disease, heart failure, hypertension, hyperlipidemia, stroke, chronic lung diseases, liver or kidney disease, adrenal diseases, musculoskeletal disorders, uncontrolled thyroid disease (dose changes within the past 3 months), Crohn's disease, Ulcerative Colitis, arthritis, undergoing active cancer treatment except for non-melanoma cancer, uncontrolled psychiatric disorder (a history of hospitalization for psychiatric illness).
* Currently taking any medication that is meant for, or has a known effect on, appetite
* On anabolic steroid or hormone replacement therapy
* Participation in an exercise/nutrition/ weight-loss program within the last 6 months
* Any history of surgical intervention for weight management
* Having a ≥5% body weight change during the last 3 months
* Pregnant or less than 6 months post-partum, breastfeeding, polycystic ovarian syndrome or irregular menstruation
* missing limbs, have a pacemaker or metal implants,
* eating disorders or EAT-26 score \>20
* Alcohol or drug addiction
* Current smoker
* Works night shifts
* Unable to commit to a 9-week study
* Not willing to follow study protocol and any other contraindications.
* Currently following any of the following restrictive diets - Keto/low carbohydrate/ Vegan/ Vegetarian/ Intermittent fasting/ Paleo/ Calorie restriction/ Any other restrictive diet
* Participating in another study
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