Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

Recruiting N/A Interventional Study
Cervical Spinal Cord Injury Tetraplegia/Tetraparesis Cervical Myelopathy
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
36 (estimated)
Sponsor
Columbia University · Other
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About This Trial

The proposed study seeks to understand how the cervical spinal cord should be stimulated after injury through short-term physiology experiments that will inform a preclinical efficacy trial. The purpose of this study is to determine which cervical levels epidural electrical stimulation (EES) should target to recruit arm and hand muscles effectively and selectively in spinal cord injury (SCI).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: •Clinical indication for cervical spine surgery. Exclusion criteria: •Stimulation devices in the neck or chest (e.g., vagal nerve stimulation, cardiac patients with pacemakers)
Contacts

Jason B Carmel, M.D., Ph.D.

917-301-1882

jbc28@cumc.columbia.edu

CONTACT

James R McIntosh, Ph.D.

212-305-6616

jrm2263@cumc.columbia.edu

CONTACT