Dexmedetomidine and Magnesium Sulfate for Cognitive Dysfunction
Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics
Recruiting
Phase 1
Interventional Study
Mental Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 60 – 80
- Sex
- Any
- Trial phase
- Phase 1
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 58 (estimated)
- Sponsor
- Fayoum University · Other
Who this trial is looking for
This trial is looking for older patients who are undergoing open abdominal surgery under general anesthesia. Participants will receive either dexmedetomidine or magnesium sulfate during their surgery to help reduce cognitive issues afterward.
Are You a Good Fit for This Trial?
You may be able to join if
- I am classified as ASA physical status I, II, or III
- I am undergoing open abdominal surgery
- I will be receiving general anesthesia
You may not be able to join if
- I have a preoperative MoCA Score below 26
- My surgery is expected to last more than 4 hours
- My BMI is more than 35 kg/m2
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Magnesium sulfate is considered a neuroprotective drug and has been studied in various applications. Recently, it has drawn the attention of anesthesiologists, resulting in numerous publications about its role in anesthesiology.
Magnesium sulfate is suggested to exert its neuroprotective effect by preventing excitotoxicity. in the clinical setting, intraoperative magnesium sulfate attenuated POCD…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* ASA physical status I, II and ⅠⅠⅠ
* patients undergoing open abdominal surgery under general anesthesia
Exclusion Criteria:
* Elderly patients with preoperative MoCA Score below 26.
* Operation time more than 4 hours to prevent excessive dosage of magnesium sulfate.
* BMI \>…
Contacts