Physiological Effects and Safety of Continuous High-frequency Oscillatory Ventilation in ICU Patients
Recruiting
N/A
Interventional Study
Atelectasis, Postoperative
Hypoxia
Critical Illness
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 Months – 80
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 45 (estimated)
- Sponsor
- Shanghai Zhongshan Hospital · Other
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About This Trial
Atelectasis, hypoxemia, and ineffective sputum clearance are common problems in ICU patients. Continuous High-Frequency Oscillation (CHFO) is often considered to have a protective effect on the lungs. CHFO provides effective gas exchange at supraphysiological frequencies while minimizing pressure fluctuations, producing tidal volumes smaller than dead space, and adjusting around a continuously exp…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients older than 18 and younger than 90 years;
* Admitted to the ICU after December 1, 2024, who are alert, with a GCS of 15, normal comprehension, and able to communicate clearly through speech or writing.
* Patients with atelectasis, who are receiving oxygen therapy, high…
Contacts