Perioperative IL-33 is Associated with the Early Stage of Postoperative Neurocognitive Dysfunction After Major Abdominal Surgery

Recruiting Observational Study
Postoperative Neurocognitive Dysfunction Cognitive Dysfunction Postoperative Complications Neuropsychological Tests
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Sex
Any
Study type
Observational
Participants needed
150 (estimated)
Sponsor
First Affiliated Hospital of Kunming Medical University · Other
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About This Trial
Perioperative neurocognitive dysfunction(PND) are common complications of major surgery among patients, could be a long-term disease, which sometimes lasts for several years, and it is meaningful to find a biomarker of PND at the early stage.As far as we know, the relationship between IL-33 and PND is not clear yet in the gastrointestinal and hepatic area. Thus, the investigators designed this stu…
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Eligibility Criteria
Inclusion Criteria:Patients were included if they had an American Society of Anesthesiologists status of Ⅱto Ⅳ and requiring a Gastrointestinal or a Hepatic surgery . Exclusion Criteria: 1. history of mental diseases; 2. patients with current Neurological disease; 3. patients who refused or were u…
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