Amniotic Suspension Allograft for Knee Osteoarthritis
Amniotic Suspension Allograft Injection for Knee Osteoarthritis
Recruiting
Phase 3
Interventional Study
Knee
Osteoarthritis
Pivotal Trial
This treatment is in the last trial phase before FDA approval.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Trial phase
- Phase 3
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 160 (estimated)
- Sponsor
- Chang Gung Memorial Hospital · Other
Who this trial is looking for
This trial is looking for adults aged 18 to 80 with knee osteoarthritis to compare different treatments. Participants will receive one of the treatments and share their experiences with pain and mobility.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 80 years old.
- I have a body mass index (BMI) less than 40.
- I have been diagnosed with knee osteoarthritis.
- I have knee pain rated greater than 4 out of 10 in the past week.
- I can walk on my own or use a cane.
You may not be able to join if
- I am pregnant or planning to become pregnant.
- I regularly take blood thinners.
- I have used pain medications other than acetaminophen recently.
- I have a history of substance abuse.
- I have had knee surgery in the last 12 months.
- I have received a specific knee injection in the last 3 months.
- I have had an organ or stem cell transplant.
- I am currently using immunosuppressive medications.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
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Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
There have been few clinical trials on ASA for the treatment of knee osteoarthritis, and there is currently no literature reporting the optimal treatment dosage. Non-surgical treatment options include braces, weight loss, lifestyle changes, oral pain relievers, and intra-articular injections. Recently, placental-derived tissues have gradually been applied in the treatment of knee osteoarthritis. T…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age between 18 and 80 years.
2. Body mass index (BMI) less than 40 kg/m².
3. Symptomatic knee osteoarthritis with X-ray evidence graded 2 or 3 on the Kellgren-Lawrence (KL) grading scale.
4. Numerical Rating Scale (NRS) score (scale 1 to 10) for pain greater than 4 over the p…
Contacts
No contact information available.