Differential Study of Invasive Pituitary Adenomas in the Sellar and Cavernous Sinus Regions
Recruiting
Observational Study
Pituitary Tumor
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Observational
- Participants needed
- 20 (estimated)
- Sponsor
- Shanghai Zhongshan Hospital · Other
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About This Trial
This study involves collecting paired tumor samples from intrasellar and cavernous sinus regions of 20 invasive pituitary tumor patients, preserving them at -80°C for quality multi-omics analysis. Proteomics and transcriptomics are employed to identify molecular differences, while imaging data (MRI/CT) assesses tumor morphology and invasion. In vitro experiments and mechanistic studies validate ke…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Invasive pituitary tumors involving the cavernous sinus
2. Retrospective inclusion of patients who have signed informed consent forms for the donation of biological samples and health-related information
3. Age range: 18-80 years
4. Subjects are willing to participate in this…
Contacts