APPI-Cost Trial for Perforated Appendicitis
Recruiting
Phase 4
Interventional Study
Perforated Appendicitis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 346 (estimated)
- Sponsor
- The University of Texas Health Science Center, Houston · Other
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About This Trial
The purpose of this study to assess the clinical effectiveness and cost-effectiveness of povidone-iodine (PVI) irrigation in perforated appendicitis, to investigate barriers and facilitators to future implementation of PVI irrigation, and to collect costs and clinical and patient-reported outcomes among patients with non-perforated appendicitis.
Trial Locations
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Eligibility Criteria
Eligibility for Enrollment
Inclusion Criteria:
* Plan to undergo appendectomy for acute appendicitis
Exclusion Criteria:
* Preoperative hemodynamic instability requiring ongoing infusion of vasopressors
* Allergy to iodine
* Uncontrolled hyper- or hypothyroidism
* Renal dysfunction
* Pregnant or…
Contacts