FIRE-Diet: Food as an Intervention to Reduce the Effects of Woodsmoke Exposure on Respiratory Health
Recruiting
N/AInterventional Study
Healthy Individuals
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
19 – 40
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
48 (estimated)
Sponsor
University of British Columbia · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Research suggests that consuming more fatty fish, fruits, and vegetables could potentially shield the lungs from the negative impacts of air pollution. The research team will look at whether a dietary intervention aimed at increasing intake of these foods can protect the lungs from woodsmoke as the air pollutant and look into how this works.
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Eligibility Criteria
Inclusion Criteria:
* Healthy, and specifically with no respiratory disease
* Not taking any supplements, or willing to abstain from supplement use for 4-weeks prior to study start and the whole duration of the study,
* Must currently consume, on average, less than 2 servings of fish per week and f…
Inclusion Criteria:
* Healthy, and specifically with no respiratory disease
* Not taking any supplements, or willing to abstain from supplement use for 4-weeks prior to study start and the whole duration of the study,
* Must currently consume, on average, less than 2 servings of fish per week and fewer than 5 servings of fruits and vegetables per day based on screening questionnaires.
* Must have a null GSTM1 genotype determined at screening.
* Must be able to provide a sufficient sputum sample during the screening visit.
Exclusion Criteria:
* Pregnant or planning to become pregnant during the study period.
* Health conditions that would pose an unacceptable risk of dietary change, or conditions that are uncontrolled based on principal investigator's judgement.
* Actively attempting to lose weight.
* Frequent wood smoke exposure (e.g. at home or employment).
* Unable to store provided meals and food safely.
* Food allergies/intolerance or food aversion preventing adherence to the intervention diet, or unwillingness/medically unable to adjust diet in line with the intervention.
* Relocation during the study period to an area which will prevent food delivery.
* History of smoking tobacco, marijuana, or and other substance or vaping within the past 6 months, or having smoked the equivalent of 0.5 pack-years ever.
* Body mass index (BMI) \<18.5, as determined during the in-person screening visit.
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