Extracellular Vesicles in Fibrin Gel for Cartilage Repair
Recruiting
Observational Study
Joint Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 51 (estimated)
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Other
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About This Trial
This project aims to produce and study in vitro/ex vivo a platelet rich plasma (PRP)-derived fibrin gel loaded with mesenchymal stromal cells (MSC)-extracellular vesicles (EVs), to combine the positive results on cartilage growth of PRP growth factors and the hyaline cartilage stimulating activity of MSC-EVs. Therefore, the project goal is to provide an advanced option for orthopedic patients with…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* males and females ≥ 18
* patients undergoing plastic surgery procedures;
* patients undergoing elective joint surgery with a diagnosis of knee or hip osteoarthritis (any Kellgren-Lawrence grade);
* patients undergoing regenerative medicine treatments with PRP with a diagnosis …
Contacts