Study of Circular RNA Treatment in Patients With Radiation Induced Xerostomia-1
Recruiting
Phase 1
Phase 2
Interventional Study
Radiation-Induced Xerostomia and Hyposalivation
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 42 (estimated)
- Sponsor
- RiboX Therapeutics Ltd. · Industry
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About This Trial
This is a first-in-human clinical study to evaluate the safety, tolerability and efficacy of RXRG001 administered in the ducts of the parotid glands in adult patients with radiation-induced xerostomia (dry mouth) and hyposalivation (reduced saliva production).
In Part 1 of the study (open-label, single-arm), patients will receive unilateral administrations of RXRG001 in 3 single ascending dose co…
Trial Locations
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Eligibility Criteria
Inclusion Criteria\*
1. At least 18 years of age
2. Free from recurrence of your cancer and never have had another form of cancer for at least 2 years
3. Suffering from xerostomia and/or hyposalivation and have xerostomia symptoms which were not resolved after treatment for at least 3 months
4. Bot…
Contacts