Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.
Recruiting
N/A
Interventional Study
Hepatic Transplantation
Rejection; Transplant, Liver
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 200 (estimated)
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna · Other
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About This Trial
Despite the good clinical results in terms of outcome with the application of HOPE prior to liver transplantation, very little is still known about the phenotypic and molecular changes that occur during perfusion/preservation during HOPE, particularly with regard to endothelial trophism and activation. Delving into these aspects would be very useful to allow personalised perfusion treatments in th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* For Donors:
Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis.
* HOPE performed on the liver graft prior to transplantation.
* For Recipients:
* Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis.
* A…
Contacts