Risk Factors Associated With the Progression of Adenomyosis
Recruiting
Observational Study
Adenomyosis
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 55
Sex
Female
Study type
Observational
Participants needed
258 (estimated)
Sponsor
IRCCS Azienda Ospedaliero-Universitaria di Bologna · Other
Who this trial is looking for
This trial is looking for women aged 18 to 55 who have adenomyosis. Participants will have their condition monitored using transvaginal ultrasound.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 18 and 55 years old.
I have been diagnosed with adenomyosis.
I can provide informed consent.
You may not be able to join if
I am undergoing a hysterectomy.
I have never had sexual intercourse.
I cannot tolerate transvaginal ultrasound.
I have a history of gynaecological cancer.
I have been pregnant or given birth in the last 6 months.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Adenomyosis is a gynaecological disorder with a high prevalence in women of childbearing age and is characterised by the presence of endometrial glands and stroma within the myometrium, associated or not with hypertrophy and hyperplasia of the surrounding myometrium. Adenomyosis may cause pelvic pain and/or abnormal uterine bleeding.
Transvaginal ultrasound (TVUS) is considered the main non-invas…
Adenomyosis is a gynaecological disorder with a high prevalence in women of childbearing age and is characterised by the presence of endometrial glands and stroma within the myometrium, associated or not with hypertrophy and hyperplasia of the surrounding myometrium. Adenomyosis may cause pelvic pain and/or abnormal uterine bleeding.
Transvaginal ultrasound (TVUS) is considered the main non-invasive diagnostic modality for the diagnosis of adenomyosis.
Although adenomyosis is a very common condition among patients of childbearing age, its natural course is still debated. Some studies have evaluated the role of hormonal treatments (systemic or local oestrogen or progestin-based) on adenomyosis, which have been effective in controlling symptoms such as pelvic pain and abnormal uterine bleeding. Despite all this, no evidence is available on the progression of adenomyosis and the factors that may influence its progression over time. The aim of this study is therefore to assess the progression of adenomyosis and associated risk factors using transvaginal ultrasound.
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Eligibility Criteria
Inclusion Criteria:
* Patients aged between 18 and 55 years;
* Presence of at least two direct and indirect signs according to the MUSA classification
* Obtaining informed consent
Exclusion Criteria:
* Patients undergoing hysterectomy;
* Virgo patients;
* Patients reporting intolerance to transva…
Inclusion Criteria:
* Patients aged between 18 and 55 years;
* Presence of at least two direct and indirect signs according to the MUSA classification
* Obtaining informed consent
Exclusion Criteria:
* Patients undergoing hysterectomy;
* Virgo patients;
* Patients reporting intolerance to transvaginal ultrasound;
* Gynaecological oncology;
* Recent pregnancy or childbirth (within 6 months)
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