The Collagen Factors of Rapid Progression of Keratoconus in Children.
Recruiting
Observational Study
Keratoconus
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 10 – 50
- Sex
- Any
- Study type
- Observational
- Participants needed
- 160 (estimated)
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University · Other
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Answer a few quick questions to see if you may meet the eligibility requirements.
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About This Trial
The purpose of this observational study was to understand the differences in clinical features and mechanisms of keratoconus between children and adults. The main questions it aimed to answer as follows: (1) to understand the characteristics of keratoconus in Chinese children. (2) to observe corneal stromal cells at the cytological level using in vivo corneal laser confocal microscopy and explore …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* ① Patients with keratoconus who visit the refractive clinic.
1. The height of the posterior corneal surface is greater than 16 microns under the Pentacam corneal topography.
2. ARTAve \< 424 microns, ARTMax \< 339 microns.
3. Clinical non-inflammatory or traumatic corne…
Contacts