Tapering Heart Failure Medications for Heart Function Recovery

Tapering Heart Failure Medication in Patients With Heart Failure With Recovered Ejection Fraction; Open Label Prospective Random Trial

Recruiting N/A Interventional Study
Heart Failure Ejection Fraction Recovery of Function
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
150 (estimated)
Sponsor
Chungnam National University Hospital · Other
Who this trial is looking for

This trial is looking for patients who have improved heart function after treatment for heart failure. Participants will either continue their current medications or work with their healthcare team to reduce them.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have an initial ejection fraction less than 40%.
  • My latest ejection fraction is over 50%.
  • I have been taking more than 3 heart failure medications.

You may not be able to join if

  • I am under 18 years old.
  • I have high blood pressure that is not controlled.
  • I have had heart surgery in the last 6 months.
  • I have severe valve disease.
  • I have an arrhythmia that needs treatment to control my heart rate.
  • I have kidney disease with protein in my urine.
  • I am pregnant.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

Study start date is on Nov 27th 2024. A patient with an initial ejection fraction (EF) of less than 40%, whose follow-up shows an improvement to an EF of 50% or higher, along with the left ventricular end-diastolic diameter returning to the normal range and taking 3 more heart failure medication randomed to drug tapering group ( RAS blocker or beta blocker) or continuing medication group.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * initial echocardiogram ejection fraction less than 40% * follow up echocardiogram ejection fraction over 50% and LVEDD index normal range * NTprobnp criteria 1. eGFR ≥60 ; less 440 2. eGFR 45-59: less 980 3. eGFR 30-44; less 1220 4. eGFR \< 30 : less 5300 5. in HD; …
Contacts

Yujin Yang

821043311245

wjsdudtns9@gmail.com

CONTACT