A Study of Lorigerlimab in Participants With Advanced Solid Tumors
Recruiting
Phase 2
Interventional Study
Platinum-resistant Ovarian Cancer
Platinum-Resistant Fallopian Tube Carcinoma
Platinum-Resistant Primary Peritoneal Carcinoma
Clear Cell Adenocarcinoma of Ovary
Clear Cell Adenocarcinoma of Vulva
Clear Cell Adenocarcinoma of Vagina
Clear Cell Adenocarcinoma of Cervix
Clear Cell Adenocarcinoma of Uterus
Clear Cell Adenocarcinoma of Fallopian Tube
Clear Cell Adenocarcinoma of Peritoneum
Endometrial Cancer
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Female
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 80 (estimated)
- Sponsor
- MacroGenics · Industry
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About This Trial
Study CP-MGD019-03 is an open-label study of lorigerlimab in participants with platinum-resistant ovarian cancer (PROC) or clear cell gynecologic cancer (CCGC). Approximately 80 participants will be enrolled. The study will assess the efficacy and safety of lorigerlimab in participants with PROC or CCGC.
Participants will receive lorigerlimab by intravenous (IV) infusion on Day 1 of every 21-day …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Histologically confirmed high-grade serous epithelial ovarian cancer, including primary peritoneal, or fallopian tube cancer, resistant to platinum based chemotherapy. OR
* Histologically confirmed clear cell carcinoma of the ovary (including primary peritoneal and fallopian t…
Contacts