A Study of Lorigerlimab in Participants With Advanced Solid Tumors

Recruiting Phase 2 Interventional Study
Platinum-resistant Ovarian Cancer Platinum-Resistant Fallopian Tube Carcinoma Platinum-Resistant Primary Peritoneal Carcinoma Clear Cell Adenocarcinoma of Ovary Clear Cell Adenocarcinoma of Vulva Clear Cell Adenocarcinoma of Vagina Clear Cell Adenocarcinoma of Cervix Clear Cell Adenocarcinoma of Uterus Clear Cell Adenocarcinoma of Fallopian Tube Clear Cell Adenocarcinoma of Peritoneum Endometrial Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Female
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
MacroGenics · Industry
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About This Trial
Study CP-MGD019-03 is an open-label study of lorigerlimab in participants with platinum-resistant ovarian cancer (PROC) or clear cell gynecologic cancer (CCGC). Approximately 80 participants will be enrolled. The study will assess the efficacy and safety of lorigerlimab in participants with PROC or CCGC. Participants will receive lorigerlimab by intravenous (IV) infusion on Day 1 of every 21-day …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Histologically confirmed high-grade serous epithelial ovarian cancer, including primary peritoneal, or fallopian tube cancer, resistant to platinum based chemotherapy. OR * Histologically confirmed clear cell carcinoma of the ovary (including primary peritoneal and fallopian t…
Contacts

Global Trial Manager

301-251-5172

info@macrogenics.com

CONTACT