RGB-5088 for Type 1 Diabetes

Phase I Clinical Study to Evaluate the Safety and Efficacy of RGB-5088 in Patients With Type 1 Diabetes Mellitus

Recruiting Phase 1 Interventional Study
Diabetes Mellitus, Type 1 Diabetes Mellitus
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 60
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
10 (estimated)
Sponsor
Hangzhou Reprogenix Bioscience, Inc · Industry
Who this trial is looking for

This trial is looking for adults with Type 1 Diabetes who have had severe low blood sugar episodes. Participants will receive islet cell transplantation to evaluate safety and effectiveness.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am 18 to 60 years old.
  • I have been diagnosed with Type 1 diabetes.
  • I have low stimulated C-peptide levels.
  • I have had at least one severe hypoglycemia in the last year.

You may not be able to join if

  • I have Type 2 diabetes.
  • I have untreated severe diabetes eye disease.
  • I have serious heart disease.
  • I have serious problems with my stomach or digestion.
  • I have serious psychological issues.
  • I have a history of cancer.
  • I abuse tobacco, alcohol, or drugs.
  • I am pregnant, breastfeeding, or unwilling to use effective birth control.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

This Phase I clinical trial is a single-center, single-arm, open-label study aimed at evaluating the safety and therapeutic efficacy of RGB-5088 islet cell transplantation in patients with Type 1 Diabetes Mellitus.

Trial Locations
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Eligibility Criteria
Key Inclusion Criteria: * Age: 18-60 years old (including 18 and 60 years old), male and female; * Type 1 diabetes patients (including those who have received organ transplantation such as liver and kidney); * Stimulated C-peptide \< 0.3 ng/mL; * The patient had at least one severe hypoglycemia wit…
Contacts

Linlin Jiang

+86+571-88601920

Linlin.jiang@reprogenix.com

CONTACT