Multicenter ALS Imaging Study
Recruiting
Observational Study
Amyotrophic Lateral Sclerosis
ALS
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 90 (estimated)
- Sponsor
- University of Minnesota · Other
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Check Your Eligibility
About This Trial
This is a multi-site study of ALS participants and healthy controls who will undergo brain and cervical spine MRIs and NfL blood testing at up-to 4 time points over the course of a year. The primary goal is to identify objective biomarkers of disease progression that are biologically relevant, linearly progressive, and sensitive to change.
Trial Locations
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Eligibility Criteria
For participants with ALS:
* \< 36 months since onset of symptoms
* Definite, probable, lab-supported probable, or possible ALS by El Escorial criteria OR definite, probable, or possible ALS per Awaji-Shima criteria OR meets Gold Coast criteria
* Forced vital capacity within the last 90 days ≥ 60% …
Contacts