This prospective study aims to evaluate the effects of mega-dose vitamin D pulse therapy followed by maintenance therapy on seizure frequency, fatigue, and quality of life in patients with epilepsy. Participants will receive vitamin D supplementation, and clinical outcomes will be assessed over time to determine its potential benefits on seizure control and patient-reported outcomes.
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Eligibility Criteria
Inclusion Criteria:
* Aged 20 or above (inclusive)
* Diagnosed patients (refractory epilepsy refers to those who have used more than two drugs, and each drug has reached the When epileptic seizures cannot be well controlled at standard reasonable treatment doses, it is called refractory epilepsy)
*…
Inclusion Criteria:
* Aged 20 or above (inclusive)
* Diagnosed patients (refractory epilepsy refers to those who have used more than two drugs, and each drug has reached the When epileptic seizures cannot be well controlled at standard reasonable treatment doses, it is called refractory epilepsy)
* There is no imaging evidence of persistence or expansion of brain damage in the past three years
* Subjects or family members (caregivers) can comply with the trial plan and take vitamin D patients
Exclusion Criteria:
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