Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients

Recruiting N/A Interventional Study
Rectal Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 80
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
270 (estimated)
Sponsor
Centre Hospitalier Universitaire Dijon · Other
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About This Trial
The adoption of total mesorectal excision (TME) has standardized rectal cancer surgery and improved oncological outcomes. In locally advanced rectal cancer, neoadjuvant radio chemotherapy (NACRT) has further improved oncological benefit. Although these strategies result in good 5-year disease-free survival rates, they are associated with significant morbidity, in particular permanent long-term bow…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patient aged 18 to 80 * Histologically proven lieberkuhnian adenocarcinoma with MSS status ; * Patient who has or is due to receive neoadjuvant treatment (4 to 6 courses of (m)FOLFIRINOX or FOLFOX chemotherapy + CAP 50 radiochemotherapy or CAP 50 radiochemotherapy alone); * BE…
Contacts

Quentin DENOST

05 47 50 15 75

q.denost@bordeaux-colorectal-institute.fr

CONTACT