Early Intervention in Plaque Psoriasis: is Bimekizumab Able to Delay Chronic Inflammation?

Recruiting Phase 2 Interventional Study
Psoriasis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 45
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
40 (estimated)
Sponsor
Centre Hospitalier Universitaire de Nice · Other
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About This Trial
Psoriasis is a chronic inflammatory condition driven by a complex interplay between heritable and microenvironmental factors. Genome-wide heritability for psoriasis (PsO) is estimated at up to 50%. Although bearing genetic susceptibility at birth, most patients will remain disease free for years until an exposomal trigger activates the immunological pathway that leads to the first disease flare. I…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Men and women 2. ≥ 18 and \<45 years 3. Plaque psoriasis without psoriatic arthritis 4. Patients with mild psoriasis PASI \>2 and \<6 5. Patient with at least one lesion on the elbows, or the knees, or the lower back to be recorded as target lesion (additional lesions in othe…
Contacts

Thierry Passeron, PhD

+33492036488

passeron.t@chu-nice.fr

CONTACT

emmanuelle PRADELLI

+33492036488

pradelli.e@chu-nice.fr

CONTACT