No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
2,396 (estimated)
Sponsor
University of Miami · Other
Who this trial is looking for
This trial is looking for patients who will undergo knee or hip surgery. Participants will help researchers understand how different types of anesthesia affect recovery outcomes.
Are You a Good Fit for This Trial?
You may be able to join if
I am having a total hip or knee surgery.
I can provide informed consent.
I speak English or Spanish.
You may not be able to join if
I have had previous back surgery with hardware.
I have high intracranial pressure.
I have an infection at the surgery site.
I have low platelet counts or blood clotting issues.
I have severe heart conditions like aortic stenosis.
I cannot provide consent.
I am currently pregnant or planning to become pregnant soon.
I am a prisoner.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this research is to compare post-operative outcomes from patients undergoing TJA. The study team wants to learn about outcomes like length of hospital stay, post-operative pain scores, post-operative nausea, deep and superficial surgical site infection, periprosthetic fracture (a broken bone that occurs around an orthopaedic implant), implant dislocation, readmission rates, and revi…
The purpose of this research is to compare post-operative outcomes from patients undergoing TJA. The study team wants to learn about outcomes like length of hospital stay, post-operative pain scores, post-operative nausea, deep and superficial surgical site infection, periprosthetic fracture (a broken bone that occurs around an orthopaedic implant), implant dislocation, readmission rates, and revision rates.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Patients undergoing a primary total hip or knee arthroplasty
* Subjects must be capable of providing informed consent
* English or Spanish speaking
Exclusion Criteria:
Patients with contraindications for spinal anesthesia such as:
* Prior lumbar surgery with hardware insert…
Inclusion Criteria:
* Patients undergoing a primary total hip or knee arthroplasty
* Subjects must be capable of providing informed consent
* English or Spanish speaking
Exclusion Criteria:
Patients with contraindications for spinal anesthesia such as:
* Prior lumbar surgery with hardware insertion
* Elevated intracranial pressure
* Infection at the site of the procedure
* Thrombocytopenia or coagulopathy
* Severe mitral and aortic stenosis and left ventricular outflow obstruction
* Severe spine pathology (spinal stenosis, spondylolisthesis, spondylosis) with radiculopathy and/or neurogenic claudication
* Preexisting neurological disease
Patients with contraindications for general anesthesia such as:
* Congestive heart failure
* Severe aortic stenosis
* Patient is unable/unwilling to consent
* Current pregnancy or women planning on becoming pregnant in the next year, and women who think they might be pregnant, or women who become pregnant during the study period will be removed from the study.
* Prisoners
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