No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
45 – 80
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
54 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for veterans with chronic obstructive pulmonary disease (COPD) to compare two types of exercise. Participants will walk either on an incline or on a flat surface to see which helps reduce breathlessness during exercise.
Are You a Good Fit for This Trial?
You may be able to join if
I am a veteran
I have been diagnosed with COPD
I have stable health
My FEV1/FVC ratio is less than 0.7
My FEV1% predicted is between 30% and 80%
My BMI is less than 35
I do not have problems like diabetes or low back pain
You may not be able to join if
I have a neurological disease
I have a musculoskeletal disease
I have a metabolic disease
I take medications that alter my mood
I need an oxygen mask at rest or during activity
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study is designed to provide information regarding how to improve pulmonary rehabilitation for persons with chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation is an exercise program for COPD patients that is recommended and benefits some, but not all, patients. The question being studied in this trial is whether during an exercise program, walking on an incline might be be…
This study is designed to provide information regarding how to improve pulmonary rehabilitation for persons with chronic obstructive pulmonary disease (COPD). Pulmonary rehabilitation is an exercise program for COPD patients that is recommended and benefits some, but not all, patients. The question being studied in this trial is whether during an exercise program, walking on an incline might be better than walking on faster on a flat surface in training muscles so that patients might be less short of breath with exercise.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Veterans from all sex/gender, race, and ethnicity will be recruited
* All subjects will undergo post-bronchodilator spirometry and be clinically stable
* All subjects must have documented FEV1/FVC ratio of \<0.7, and between 30% to 80% FEV1% predicted
* If subjects have non-qu…
Inclusion Criteria:
* Veterans from all sex/gender, race, and ethnicity will be recruited
* All subjects will undergo post-bronchodilator spirometry and be clinically stable
* All subjects must have documented FEV1/FVC ratio of \<0.7, and between 30% to 80% FEV1% predicted
* If subjects have non-qualifying spirometry, they will not be screened further
* Subjects with qualifying spirometry will be screened further
* Potential subjects must have a BMI of less than 35 kg/m2 and must be free from co-morbidities that may affect walking patterns
* e.g., peripheral arterial disease, diabetes, low back pain
Exclusion Criteria:
* Confounding effects such as neurological, musculoskeletal, or metabolic disease
* Subjects taking medications that alter mood or metabolic demand will be excluded
* All potential subjects must be cleared for participation by a physician after undergoing a cardiopulmonary exercise test
* Require an O2 mask during rest or activity
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